Richard, V.R., Bourque, S.D. and Titorenko, V.I.Metabolomic and lipidomic analyses of chronologically aging yeast. In: Yeast Genetics. Methods and Protocols.Eds. Smith, J.S. and Burke, D.J. Humana Press, USA, pp. 359-373 (2014).
Boukh-Viner, T. and Titorenko, V.I. Lipids and lipid domains in the peroxisomal membrane of the yeast Yarrowia lipolytica. Biochem. Biophys. Acta (2006) 1763:1688-1696. 2005 Boukh-Viner, T., Guo, T., Alexandrian, A., Cerracchio, A., Gregg, C., Haile, S., Kyskan, R., Milijevic, S., Oren, D., Solomon, J., Wong, V., Nicaud, J.-M., Rachubinski, R.A., English, A.M. and Titorenko, V.I. Dynamic ergosterol- and ceramide-rich domains in the peroxisomal membrane serve as an organizing platform for peroxisome fusion. J. Cell Biol. (2005) 168:761-773. 2004 Titorenko, V.I. and Rachubinski, R.A. The peroxisome: orchestrating important developmental decisions from inside the cell. J. Cell Biol. (2004) 164:641-645. Petriv, O.I., Tang, L., Titorenko, V.I. and Rachubinski, R.A. A new definition for the consensus sequence of the peroxisome targeting signal type 2. J. Mol. Biol. (2004) 341:119-134. 2003 Guo, T., Kit, Y.Y., Nicaud, J.-M., Le Dall, M.-T., Sears, S.K., Vali, H., Chan, H., Rachubinski, R.A.and Titorenko, V.I. Peroxisome division is regulated by a signal from inside the peroxisome. J. Cell Biol. (2003) 162:1255-1266. Barth, G., Beckerich, J.-M., Dominguez, A., Kerscher, S., Ogrydziak, D., Titorenko, V.I. and Gaillardin, C. Functional genetics of Yarrowia lipolytica. In: Functional Genetics of Industrial Yeasts. Series: Topics in Current Genetics, Vol. 2, ed. J.H. de Winde. Springer-Verlag Heidelberg, Germany, pp. 227-272 (2003). 2002 Titorenko, V.I., Nicaud, J.-M., Wang, H., Chan, H. and Rachubinski, R.A. Acyl-CoA oxidase is imported as a heteropentameric, cofactor-containing complex into peroxisomes of Yarrowia lipolytica. J. Cell Biol. (2002) 156:481-494. Petriv, O.I., Pilgrim, D.B., Rachubinski, R.A. and Titorenko, V.I. RNA interference of peroxisome-related genes in C. elegans: a new model for human peroxisomal disorders.Physiol. Genomics (2002) 10:79-91. 2001 Titorenko, V.I. and Rachubinski, R.A. Dynamics of peroxisome assembly and function. Trends Cell Biol. (2001) 11:22-29. Titorenko, V.I. and Rachubinski, R.A. The life cycle of the peroxisome. Nature Rev. Mol. Cell Biol. (2001) 2:357-368. The above review article was highlighted and recommended for reading in a cell biology textbook, the 4th edition of "The Cell: A Molecular Approach" by G.M. Cooper and R.E. Hausman (Sinauer Associates, Inc., Sunderland, MA) published in 2007. 2000 Brown, T.W., Titorenko, V.I. and Rachubinski, R.A. Mutants of the Yarrowia lipolyticaPEX23gene encoding an integral peroxisomal membrane peroxin mislocalize matrix proteins and accumulate vesicles containing peroxisomal matrix and membrane proteins. Mol. Biol. Cell(2000) 11:141-152. Titorenko, V.I., Chan, H. and Rachubinski, R.A. Fusion of small peroxisomal vesicles in vitro reconstructs an early step in the in vivo multistep peroxisome assembly pathway of Yarrowia lipolytica. J. Cell Biol. (2000) 148:29-43. The above article was an Editors' Choice article in Science (2000) 287:549. Titorenko, V.I. and Rachubinski, R.A. Peroxisomal membrane fusion requires two AAA family ATPases, Pex1p and Pex6p. J. Cell Biol. (2000) 150:881-886. Titorenko, V.I., Smith, J.J., Szilard, R.K. and Rachubinski, R.A. Peroxisome biogenesis in the yeast Yarrowia lipolytica. Cell Biochem. Biophys. (2000) 32:21-26. 1999 Kiel, J.A.K.W., Rechinger, K.B., van der Klei, I.J., Salomons, F.A., Titorenko, V.I. and Veenhuis, M. The Hansenula polymorpha PDD1 gene product, essential for the selective degradation of peroxisomes, is a homologue of Saccharomyces cerevisiae Vps34p. Yeast (1999) 15:741-754. 1998 Titorenko, V.I. and Rachubinski, R.A. Mutants of the yeast Yarrowia lipolytica defective in protein exit from the endoplasmic reticulum are also defective in peroxisome biogenesis. Mol. Cell. Biol. (1998) 18:2789-2803. The above article was selected by the American Society for Microbiology (ASM) as an article of the year published in ASM Journals. Titorenko, V.I. and Rachubinski, R.A. The endoplasmic reticulum plays an essential role in peroxisome biogenesis. Trends Biochem. Sci. (1998) 23:231-233. The above review article was highlighted and recommended for reading in the cell biology texbook "Cells" by B. Lewin, L. Cassimeris, V.R. Lingappa and G. Plopper (Jones and Barlett Publishers, Inc., Sudbury, MA) published in 2007. Titorenko, V.I., Smith, J.J., Szilard, R.K. and Rachubinski, R.A. Pex20p of the yeast Yarrowia lipolytica is required for the oligomerization of thiolase in the cytosol and for its targeting to the peroxisome. J. Cell Biol. (1998) 142:403-420. 1997 Titorenko, V.I., Ogrydziak, D.M. and Rachubinski, R.A. Four distinct secretory pathways serve protein secretion, cell surface growth, and peroxisome biogenesis in the yeast Yarrowia lipolytica. Mol. Cell. Biol. (1997) 17:5210-5226. 1996 Gruzman, M.B., Titorenko, V.I., Ashin, V.V., Lusta, K.A. and Trotsenko, Y.A. Multiple molecular forms of alcohol oxidase from the methylotrophic yeast Pichia methanolica. Biochemistry (Moscow) (1996) 61:1537-1544. Titorenko, V.I., Evers, M.E., Diesel, A., Samyn, B., van Beeumen, J., Roggenkamp, R., Kiel, J.A.K.W., van der Klei, I.J. and Veenhuis, M. Identification and characterization of cytosolic Hansenula polymorpha proteins belonging to the HSP70 protein family. Yeast (1996) 12:849-857. Eitzen, G.A., Titorenko, V.I., Smith, J.J., Veenhuis, M., Szilard, R.K. and Rachubinski, R.A. The Yarrowia lipolytica gene PAY5 encodes a peroxisomal integral membrane protein homologous to the mammalian peroxisome assembly factor PAF-1. J. Biol. Chem. (1996) 271:20300-20306. Titorenko, V.I., Eitzen, G.A. and Rachubinski, R.A. Mutations in the PAY5 gene of the yeast Yarrowia lipolytica cause the accumulation of multiple subpopulations of peroxisomes. J. Biol. Chem. (1996) 271:20307-20314. Evers, M.E., Titorenko, V.I., Harder, W., van der Klei, I.J. and Veenhuis, M. Flavine adenine dinucleotide binding is the crucial step in alcohol oxidase assembly in the yeast Hansenula polymorpha. Yeast (1996) 12:917-923. 1995 Titorenko, V.I., Keizer, I., Harder, W. and Veenhuis, M. Isolation and characterization of mutants impaired in the selective degradation of peroxisomes in the yeast Hansenula polymorpha. J. Bacteriol. (1995) 177:357-363. van der Klei, I.J., Hillbrands, R.E., Swaving, G.J., Waterham, H.R., Vrieling, E.G., Titorenko, V.I., Cregg, J.M., Harder, W. and Veenhuis, M. The Hansenula polymorphaPER3 gene is essential for the import of PTS1 proteins into the peroxisomal matrix. J. Biol. Chem. (1995) 270:17229-17236. Tan, X., Titorenko, V.I., van der Klei, I.J., Sulter, G.J., Haima, P., Waterham, H.R., Evers, M., Harder, W., Veenhuis, M. and Cregg, J.M. Characterization of peroxisome-deficient mutants of Hansenula polymorpha. Curr. Genet. (1995) 28:248-257. Szilard, R.K., Titorenko, V.I., Veenhuis, M. and Rachubinski, R.A. Pay32p of the yeast Yarrowia lipolytica is an intraperoxisomal component of the matrix protein translocation machinery. J. Cell Biol. (1995) 131:1453-1469. Titorenko, V.I., Evers, M.E., van der Klei, I.J., Harder, W. and Veenhuis, M. Restoration of peroxisome formation in two conditional peroxisome-deficient mutants of Hansenulapolymorpha during growth of cells on specific organic nitrogen sources. Yeast (1995) 11:1139-1145. 1994 Evers, M.E., Titorenko, V.I., van der Klei, I.J., Harder, W. and Veenhuis, M. Assembly of alcohol oxidase in peroxisomes of the yeast Hansenula polymorpha requires the cofactor flavine adenine dinucleotide. Mol. Biol. Cell (1994) 5:829-837. Waterham, H.R., Titorenko, V.I., Haima, P., Cregg, J.M., Harder, W. and Veenhuis, M. The Hansenula polymorpha PER1 gene is essential for peroxisome biogenesis and encodes a peroxisomal matrix protein with both carboxy- and amino-terminal targeting signals. J. Cell Biol. (1994) 127:737-749. 1993 Evers, M.E., Huhse, B., Titorenko, V.I., Kunau, W.H., Hartl, F.-U., Harder, W. and Veenhuis, M. Affinity purification of molecular chaperones of the yeast Hansenula polymorpha using immobilized denatured alcohol oxidase. FEBS Lett. (1993) 321:32-36. Titorenko, V.I., Waterham, H.R., Cregg, J.M., Harder, W. and Veenhuis, M. Peroxisome biogenesis in the yeast Hansenula polymorpha is controlled by a complex set of interacting gene products. Proc. Natl. Acad. Sci. USA (1993) 90:7470-7474. Waterham, H.R., Titorenko, V.I., Swaving, G.J., Harder, W. and Veenhuis, M. Peroxisomes in the methylotrophic yeast Hansenula polymorpha do not necessarily derive from pre-existing organelles. EMBO J. (1993) 12:4785-4794. An electron micrograph from this article was a cover illustration on the December 1993 issue of the EMBO J. 1992 Titorenko, V.I., Waterham, H.R., Haima, P., Harder, W. and Veenhuis, M. Peroxisome biogenesis in Hansenula polymorpha: different mutations in genes, essential for peroxisome biogenesis, cause different peroxisomal mutant phenotypes. FEMS Microbiol. Lett. (1992) 95:143-148. Veenhuis, M., van der Klei, I.J., Titorenko, V.I. and Harder, W. Hansenula polymorpha: an attractive model organism for molecular studies of peroxisome biogenesis and function. FEMS Microbiol. Lett. (1992) 100:393-404. Waterham, H.R., Titorenko, V.I., van der Klei, I.J., Harder, W. and Veenhuis, M. Isolation and characterization of peroxisomal protein import (Pim-) mutants of Hansenula polymorpha. Yeast (1992) 8:961-972. 1991 Titorenko, V.I., Khodursky, A.B., Teslyar, G.E. and Sibirny, A.A. Identification of new genes involved in catabolite repression of alcohol oxidase and catalase synthesis in the methylotrophic yeast Pichia pinus.Genetika (1991) 27:625-635. Titorenko, V.I., Khodursky, A.B. and Sibirny, A.A. Properties of new mutants of the methylotrophic yeast Pichia pinus impaired in catabolite repression. Genetika (1991) 27:791-800. Sibirny, A.A., Titorenko, V.I., Teslyar, G.E., Petrushko, V.I. and Kucher, M.M. Methanol and ethanol utilization in methylotrophic yeast Pichia pinus wild-type and mutant strains. Arch. Microbiol. (1991) 156:455-462. 1990 Sibirny, A.A., Ubiyvovk, V.M., Gonchar, M.V., Titorenko, V.I., Voronovsky, A.Y., Kapultsevich, Y.G. and Bliznik, K.M. Reactions of direct formaldehyde oxidation to CO2 are non-essential for energy supply of yeast methylotrophic growth. Arch. Microbiol. (1990) 154:566-575. Titorenko, V.I., Motruk, O.M., Efremov, B.D., Petrushko, V.I., Teslyar, G.E., Kulachkovsky, A.R., Sibirny, A.A. and Tolstorukov, I.I. Selection and properties of the mutants of methylotrophic yeast Pichia pinus defective in alcohol dehydrogenase and formaldehyde reductase. Genetika (1990) 26:1749-1759. Gonchar, M.V., Titorenko, V.I., Gladarevskaya, N.N. and Sibirny, A.A. The phenomenon of the medium acidification by methylotrophic yeast cells and its biochemical nature. Biochemistry (Moscow) (1990) 55:2148-2158. Kulachkovsky, A.R., Titorenko, V.I. and Sibirny, A.A. Electron microscopical investigation of the mutants of the methylotrophic yeast Pichia pinus impaired in different steps of ethanol metabolism. Tsitologiya i Genetika (1990) 24:17-20. Sibirny, A.A. and Titorenko, V.I. Molecular mechanisms of catabolite regulation in yeasts. VINITI Press, Molecular Biology, Moscow, USSR, 214 pages (1990). 1989 Titorenko, V.I. and Sibirny, A.A. Carbon catabolite inactivation in yeast as an important way of regulation at the posttranslational level (Review). Biopolymeri i Kletka (1989) 5:23-36. Tolstorukov, I.I., Efremov, B.D., Benevolensky, S.V., Titorenko, V.I. and Sibirny, A.A. Mutants of the methylotrophic yeast Pichia pinus defective in C2-metabolism. Yeast (1989) 5:179-186. Titorenko, V.I. and Sibirny, A.A. Laboratory course of methods in yeast genetics. Lvov University Press, Lvov, USSR, 116 pages (1989). 1988 Sibirny, A.A., Titorenko, V.I., Gonchar, M.V., Ubiyvovk, V.M., Ksheminskaya, G.P. and Vitvitskaya, O.P. Genetic control of methanol utilization in yeasts. J. Basic Microbiol. (1988) 28:293-319. Sibirny, A.A. and Titorenko, V.I. Inhibition of isocitrate lyase and malate synthase induction in Pichia pinus yeast by methanol. Biotekhnologiya (1988) 4:194-196. 1987 Sibirny, A.A., Titorenko, V.I., Efremov, B.D. and Tolstorukov, I.I. Multiplicity of mechanisms of carbon catabolite repression involved in the synthesis of alcohol oxidase in the methylotrophic yeast Pichia pinus. Yeast (1987) 3:233-241. Sibirny, A.A., Titorenko, V.I. and Ubiyvovk, V.M. Differences in the regulation of biosynthesis of cytosolic superoxide dismutase and methanol oxidation enzymes in yeasts. Biochemistry (Moscow) (1987) 52:469-473. 1986 Sibirny, A.A. and Titorenko, V.I. A method of quantitative determination of alcohol oxidase and catalase in yeast colonies. Ukr. Biokhim. Zhurn. (1986) 58:65-68. Sibirny, A.A., Titorenko, V.I., Benevolensky, S.V. and Tolstorukov, I.I. On regulation of methanol metabolism in the mutant of Pichia pinus yeast deficient in isocitrate lyase. Biochemistry (Moscow) (1986) 51:16-22. Sibirny, A.A., Titorenko, V.I., Benevolensky, S.V. and Tolstorukov, I.I. On the differences in the mechanisms of ethanol- and glucose-induced catabolite repression in the yeast Pichia pinus. Genetika (1986) 22:584-592. Titorenko, V.I., Mikityuk, R.G., Motruk, O.M. and Sibirny, A.A. Influence of different carbon sources on methanol metabolism in the methylotrophic yeast Pichia pinus. In: Physiology, Genetics and Biochemistry of Methylotrophic Microorganisms, Naukova Dumka Press, Kiev, USSR, pp. 29-33 (1986). 1983 Titorenko, V.I., Bykovskaya, S.V. and Trotsenko, Yu. A. Characterization of mutants and genetic control of methanol metabolism in Candida boidinii. Mikrobiologiya (1983) 52:307-311. Titorenko, V.I. and Trotsenko, Yu. A. Selection of the branched-chain amino acid producing mutants in the methylotrophic yeast Hansenula polymorpha. Mikrobiologiya (1983) 52:979-985. 1982 Titorenko, V.I. Selection of mutants of the methylotrophic yeast Candida boidinii using an indicator media with phloxine. Mikrobiologiya (1982) 51:161-163.
